APERTUM
NEURO

About Apertum Neuro

Repeat founders.
A new delivery problem.

Apertum is being built by the co-founders of Actipulse Neuroscience: a complementary operator-scientist team with experience moving non-invasive neurotechnology from research into clinical workflows.

Visit Actipulse Neuroscience
2017Actipulse founded
W22Y Combinator batch
15kpatients treated
Adrien Châtillon, co-founder and CEO of Apertum Neuro
01

Co-founder & Chief Executive Officer

Adrien
Châtillon

A health-technology entrepreneur focused on making neurotechnology more accessible—and on turning scientific capability into scalable companies.

Adrien earned a Master in International Business from Grenoble École de Management in 2013. He is a serial entrepreneur who has founded more than three startups and lived or worked across more than eight countries.

He co-founded Actipulse Neuroscience in 2017 and led the company through Y Combinator’s Winter 2022 batch. His operating thesis is direct: build medical technology around access, affordability and practical clinical adoption.

Gabriel Villafuerte Jiménez, co-founder and CSO of Apertum Neuro
02

Co-founder & Chief Scientific Officer · MD, PhD

Gabriel
Villafuerte

A physician-neuroscientist working across neuromodulation, neurodegeneration and the translation of brain research into usable devices and protocols.

Gabriel graduated with honors from the UNAM Faculty of Medicine and completed a doctorate in neuroscience at UNAM after research in neuroimmunology and neural plasticity. His doctoral work examined conscious olfactory perception and orbitofrontal-cortex modulation.

At Actipulse he has led scientific and clinical work on low-intensity transcranial magnetic stimulation. Peer-reviewed studies bearing his authorship include a 2021 six-month Alzheimer’s pilot and a 2025 randomized crossover study reporting transient gamma-oscillation modulation.

Operating experience
meets mechanistic depth.

Actipulse centered on therapeutic neuromodulation. Apertum applies the team’s device, clinical and regulatory experience to a different bottleneck: temporarily changing the access condition around a systemic therapeutic while keeping the therapeutic itself unchanged.

Explore Actipulse

Follow their
work.